Transitional lncRNA Signatures Reveal Distinct Stages of Cancer Progression and Metastasis

Abstract excerpt

<title>Abstract</title> <p>Long non-coding RNAs (lncRNAs) are emerging as key regulators in cancer, influencing gene expression, chromatin remodeling, and signaling. Evidence from The Cancer Genome Atlas (TCGA) and other datasets supports their role in tumor progression. Although the human genome harbors thousands lncRNA genes, only a small subset has been validated in cancer. In this study, we used the LncBook c...

Topics

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• Autophagy
• Enhancer Elements, Genetic
• Epithelial-Mesenchymal Transition
• Internet
• RNA, Circular
• RNA, Long Noncoding
• RNA, Neoplasm
• Single-Cell Analysis

Identifiers and source

Literature Corpus work

878ad8a7-5bf1-59e3-8a84-fb1aa50736d0

DOI

10.21203/rs.3.rs-6832311/v1