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Article

Zebrafish patient-derived xenograft system for predicting carboplatin resistance and metastasis of ovarian cancer

9 Nov 2024

Abstract excerpt

AIMS: Ovarian cancer (OC) remains a significant challenge in oncology due to high rates of drug resistance and disease relapse following standard treatment with surgery and platinum-based chemotherapy. Despite the widespread use of these treatments, no effective biomarkers currently exist to identify which patients will respond favorably to therapy. This study introduces a zebrafish patient-derived xenograft...

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PMID: 39571238
DOI: 10.1016/j.drup.2024.101162

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