Article

Reconstruction and exploitation of a dedicated Genome-Scale Metabolic Model of the human pathogen <i>C. neoformans</i>

2025-04-08

Abstract excerpt

C. neoformans is notorious for causing severe pulmonary and central nervous system infections, particularly in immunocompromised patients. High mortality rates, associated with its tropism and adaptation to the brain microenvironment and its drug resistance profile, makes this pathogen a public health threat and a World Health Organization (WHO) priority. In this study, we reconstructed GSMM iRV890 for C. neofor...

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Literature Corpus work: 10e7724d-455b-5dcf-b9e0-a6f058c4adf3
DOI: 10.1101/2025.04.02.646762

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