Back to search

Article

A miR-494 dependent feedback loop regulates ER stress

2020-05-13

Abstract excerpt

Defects in stress responses are important contributors in many chronic conditions including cancer, cardiovascular disease, diabetes, and obesity-driven pathologies like non-alcoholic steatohepatitis (NASH). Specifically, endoplasmic reticulum (ER) stress is linked with these pathologies and control of ER stress can ameliorate tissue damage. MicroRNAs have a critical role in regulating diverse stress responses inc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
10d20b69-54c4-5594-bf06-48fcb16f4068
DOI
10.1101/2020.05.12.088856
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A miR-494 dependent feedback loop regulates ER stressDOI 10.1101/2020.05.12.088856
Endoplasmic reticulum stress signaling: the microRNA connectionSemantic proximity
The Unfolded Protein Response in Health and DiseaseSemantic proximity
Regulation of the unfolded protein response by noncoding RNASemantic proximity
Endoplasmic reticulum stress in the pathogenesis of fibrotic diseaseSemantic proximity
Micro(RNA)managing Endoplasmic Reticulum StressSemantic proximity
Impact of Obesity-Related Endoplasmic Reticulum Stress on Cancer and Associated Molecular TargetsSemantic proximity
The two faces of miR-29.Semantic proximity
Integrative view of serpins in health and disease: the contribution of serpinA3Semantic proximity
The unfolded protein response transducer IRE1α prevents ER stress‐induced hepatic steatosisSemantic proximity
Sephin1 rewires proteostasis through actin-dependent signalingSemantic proximity
Discovery of a molecular glue that enhances UPR <sup>mt</sup> to restore proteostasis <i>via</i> TRKA-GRB2-EVI1-CRLS1 axisSemantic proximity
Regulation of the ER stress response by a mitochondrial microproteinSemantic proximity
Select a neighboring publication to make it the new centre.