Article

Adenoviral-mediated gene transfer into the scala media of the mouse cochlea in vivo

2026-04-29

Abstract excerpt

Gene therapy may provide a way to restore inner ear function to deaf and dizzy patients. The mouse is a crucial model system for functional genomics because of the numerous genetic models for hearing loss and inner ear dysfunction. Using an advance generation, E1-/E3-/E2b-(preterminal protein-/polymerase-) Type 5 Adenovirus, we investigated several routes of virus microinjection to determine which were most reprod...

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Literature Corpus work: 10484ba2-e785-5e82-aad8-38529683d26d
DOI: 10.64898/2026.04.25.720849

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