Article

The glucocorticoid receptor elicited proliferative response in human erythropoiesis is BCL11A-dependent

2024-02-08

Abstract excerpt

<h4>ABSTRACT</h4> Prior evidence indicates that the erythroid cellular response to glucocorticoids (GC) has developmental specificity, namely, that developmentally more advanced cells that are undergoing or have undergone fetal to adult globin switching are more responsive to GC-induced expansion. To investigate the molecular underpinnings of this, we focused on the major developmental globin regulator BCL11A. We...

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Literature Corpus work: 0fedd441-5ca2-5891-9bad-254b0dd07068
DOI: 10.1101/2024.02.05.577972

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