Article

Aging-associated weakening of the action potential in fast-spiking interneurons in the human neocortex

2024-03-27

Abstract excerpt

<h4>ABSTRACT</h4> Aging is associated with the slowdown of neuronal processing and cognitive performance in the brain; however, the exact cellular mechanisms behind this deterioration in humans are poorly elucidated. Recordings in human acute brain slices prepared from tissue resected during brain surgery enable the investigation of neuronal changes with age. Although neocortical fast-spiking cells are widely imp...

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Literature Corpus work: 0fc5d83b-d7e7-5978-8225-2820115766d1
DOI: 10.1101/2024.03.24.586453

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