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Article

Brain gene expression in a novel mouse model of postpartum mood disorder

2019-02-20

Abstract excerpt

<h4>Introduction</h4> Steroid sulfatase (STS) is an enzyme which cleaves sulfate groups from a variety of steroid hormones, thereby altering their activity and solubility. The expression and activity of STS is increased in female mammalian tissues (including brain) during late pregnancy and into the postpartum period. STS-deficient human and mouse mothers (as a consequence of genetic mutation or acute pharmacolog...

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Literature Corpus work
0f6b3f84-b823-5b4f-bf89-9b97ace35667
DOI
10.1101/555870
Open publication

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