Article

Regulation of Iron Homeostasis Through Parkin-mediated Lactoferrin Ubiquitylation

2020-06-05

Abstract excerpt

<h4>ABSTRACT</h4> Somatic mutations that perturb Parkin ubiquitin ligase activity and the misregulation of iron homeostasis have both been linked to Parkinson’s disease. Lactotransferrin is a member of the transferrin iron binding proteins that regulate iron homeostasis and increased levels of Lactotransferrin and its receptor have been observed in neurodegenerative disorders like Parkinson’s disease. Here, we re...

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Literature Corpus work: 0f2ac932-da8d-5cfb-9a73-c591f4a4ba53
DOI: 10.1101/2020.06.04.133637

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