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Article

Structure and Function of Fbxo7/PARK15 in Parkinson's Disease.

Current protein & peptide science - 1 Jan 2017

Randle Suzanne J, Laman Heike

Abstract excerpt

Fbxo7/PARK15 has well-defined roles, acting as part of a Skp1-Cul1-F box protein (SCF)- type E3 ubiquitin ligase and also having SCF-independent activities. Mutations within FBXO7 have been found to cause an early-onset Parkinson's disease, and these are found within or near to its functional domains, including its F-box domain (FBD), its proline rich region (PRR), and its ubiquitinlike domain (Ubl). We highlight...

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Source

Identifiers

PMID: 26965690
DOI: 10.2174/1389203717666160311121433

Genes

FBXO7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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