Article

Abplatin(IV) Inhibited Tumor Growth On A Patient Derived Cancer Model of Hepatocellular Carcinoma And Its Comparative Multi-Omics Study With Cisplatin

2022-01-07

Abstract excerpt

<h4>Background: </h4> Cisplatin is the most common antitumor alkylating agent of platinum(II) (Pt(II)) in clinic, however it had many side effects. It is necessary to develop low toxicity platinum(IV) (Pt(IV)) drugs. Multi-omics was frequently used to help one understand the mechanism of a certain therapy at the molecular level. Little was known about the mechanism of Pt(IV) drugs, which may be benifical for clini...

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Literature Corpus work: a356d4de-e68b-5baa-8a9c-da03f6c82fb6
DOI: 10.21203/rs.3.rs-1207967/v1

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