Article

Sevoflurane Exposure of Clinical Dose in Pregnant Rat Induces Vcan Changes Without Significant Neural Apoptosis in the Offspring

2021-07-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Sevoflurane is a commonly used inhalational anesthetic in clinic. Prolonged exposure to sevoflurane can induce significant changes in lipid metabolism and neuronal damage in the developing brain. However, the effect of sevoflurane exposure of clinical dose in pregnant rat remains unclear. <bold>Results</bold>: The following study was to explore lipidomics and tr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0ea32358-0931-5633-bf2b-485961c054c2
DOI: 10.21203/rs.3.rs-680573/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sevoflurane Exposure of Clinical Dose in Pregnant Rat Induces Vcan Changes Without Significant Neural Apoptosis in the OffspringDOI 10.21203/rs.3.rs-680573/v1Read

Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevofluraneSemantic proximity Read

Genome-Wide Screen of the Hippocampus in Aged Rats Identifies Mitochondria, Metabolism and Aging Processes Implicated in Sevoflurane AnesthesiaSemantic proximity Read

Changes in microRNA expression in rat lungs caused by sevoflurane anesthesia: a TaqMan^|^reg; low-density array studySemantic proximity Read

Sevoflurane promotes premature differentiation of dopaminergic neurons in hiPSC-derived midbrain organoidsSemantic proximity Read

Effects of Sevoflurane on the Development of a Human Brain Microphysiological SystemSemantic proximity Read

Rosiglitazone promotes oligodendrocyte development and myelin formation of repeated neonatal sevoflurane exposure via PPARγ signalingSemantic proximity Read

RETRACTED: Exploring causative gene and pathway of sevoflurane-induced anesthetic effects and implication on nervous system diseases based on high-throughput scRNA-seq dataSemantic proximity Read

Sevoflurane aggravated neuroinflammation and oxidative stress in neonatal mice by modulating microglia phenotype via circRNA2092/miR-873a-5p/KEAP1.Semantic proximity Read

Repeated Neonatal Sevoflurane Induced Neurocognitive Impairment Through NF-κB-Mediated PyroptosisSemantic proximity Read

Identification of differential m6A RNA methylomes and ALKBH5 as a potential prevention target in the developmental neurotoxicity induced by multiple sevoflurane exposuresSemantic proximity Read

Whole-exome sequencing reveals genetic variations in humans with differential sensitivity to sevoflurane：A prospective observational study.Semantic proximity Read

Neonatal anesthesia and dysregulation of the epigenomeSemantic proximity Read