Article

Molecular Basis of IGHG4-Related Low Serum IgG4 Subclasses in Down Syndrome

2022-03-30

Abstract excerpt

<h4>Background: </h4> Patients with Down syndrome (DS) are more likely to exhibit immunological abnormalities that predispose them to infection. Among other anomalies, individuals with DS have altered serum concentrations of some subclasses of Immunoglobulin G (IgG), particularly the IgG4 subclasses The aim of the present study was to investigate the molecular mechanism of low serum IgG4 at the level of the heavy...

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Literature Corpus work: 0e7c3827-cc1a-5382-8692-73c23e63f1cd
DOI: 10.22541/au.164864367.78710917/v1

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