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Article

Immune Defect in Adults With Down Syndrome: Insights Into a Complex Issue.

Frontiers in immunology - 1 Jan 2020

Dieudonné Yannick, Uring-Lambert Beatrice, Jeljeli Mohamed Maxime, Gies Vincent, Alembik Yves, Korganow Anne-Sophie, Guffroy Aurélien

Abstract excerpt

Children with Down syndrome (DS) suffer from recurrent respiratory infections, which represent the leading cause of mortality during childhood. This susceptibility to infections is usually considered multifactorial and related to both impaired immune function and non-immunological factors. Infections are also one of the top causes of death in DS at adulthood. DS is considered an immunodeficiency with syndromic...

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Source

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Identifiers

PMID: 32457756
DOI: 10.3389/fimmu.2020.00840
PMCID: PMC7225335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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