Article
Multi-Omics Assessment of Genetic Risk for Celiac Disease in Down Syndrome
2022-09-29
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Objectives</h4> Individuals with Down syndrome (DS) display high risk of celiac disease (CD), but the mechanisms underlying this increased susceptibility await elucidation. Here, we examined the prevalence of HLA genotypes associated with CD risk in the general population and tested a previously developed genetic risk score (GRS) for CD in people with DS. <h4>Methods</h4> HLA genotypes wer...
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Identifiers and source
- Literature Corpus work
- 926ebe73-8bcf-530f-a9d1-dfda4e330cec
- DOI
- 10.1101/2022.09.27.22280436