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Article

Interleukin 6 and 10 Serum Levels and Genetic Polymorphisms in Children with Down Syndrome.

Mediators of inflammation - 1 Jan 2018

Mattos Marlon Fraga, Biselli-Chicote Patrícia Matos, Biselli Joice Matos, da Silva Assembleia Thiago Luís, Goloni-Bertollo Eny Maria, Pavarino Érika Cristina

Abstract excerpt

Immunological impairment is a condition that is often observed in individuals with Down syndrome (DS). The immune response is modulated by pro- and anti-inflammatory cytokines whose expressions could be influenced by genetic polymorphisms. The present study was aimed at evaluating the frequencies of -174G>C, -572G>C, and -597G>A polymorphisms in the interleukin 6 (IL-6) gene and -592C>A, -1082A>G, and -819C>T...

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Share to Polymorphism, Single Nucleotide
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Down Syndrome

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Share to Promoter Regions, Genetic

Source

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Identifiers

PMID: 30186038
DOI: 10.1155/2018/6539548
PMCID: PMC6116409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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