Article

An Open Microfluidic Coculture Model of Fibroblasts and Eosinophils to Investigate Mechanisms of Airway Inflammation

2022-07-11

Abstract excerpt

Interactions between fibroblasts and immune cells play an important role in tissue inflammation. Previous studies have found that eosinophils activated with interleukin-3 (IL-3) degranulate on aggregated immunoglobulin G (IgG) and release mediators that activate fibroblasts in the lung. However, these studies were done with eosinophil-conditioned media that have the capacity to investigate only one-way signaling f...

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Literature Corpus work: 0e766825-f136-50bb-bebc-bf19c8694cc9
DOI: 10.1101/2022.07.11.499658

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