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Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia

11 Mar 2020

Abstract excerpt

Neutrophil extracellular traps (NETs) provide host defense but can contribute to the pathobiology of diverse human diseases. We sought to determine the extent and mechanism by which NETs contribute to human airway cell inflammation. Primary normal human bronchial epithelial cells (HBEs) grown at air-liquid interface and wild-type (wt)CFBE41o- cells (expressing wtCFTR) were exposed to cell-free NETs from unrelated...

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PMID: 32159969
DOI: 10.1152/ajplung.00144.2019

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