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Article

Fast-track development of an in vitro 3D lung/immune cell model to study Aspergillus infections.

Scientific reports - 14 Sept 2017

Chandorkar P, Posch W, Zaderer V, Blatzer M, Steger M, Ammann C G, Binder U, Hermann M, Hörtnagl P, Lass-Flörl C, Wilflingseder D

Abstract excerpt

To study interactions of airborne pathogens, e.g. Aspergillus (A.) fumigatus with upper and lower respiratory tract epithelial and immune cells, we set up a perfused 3D human bronchial and small airway epithelial cell system. Culturing of normal human bronchial or small airway epithelial (NHBE, SAE) cells under air liquid interphase (ALI) and perfusion resulted in a significantly accelerated development of the...

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Identifiers

PMID: 28912507
DOI: 10.1038/s41598-017-11271-4
PMCID: PMC5599647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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