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Article

Quantitative genome-scale analysis of human liver reveals dysregulation of glycosphingolipid pathways in progressive nonalcoholic fatty liver disease

2021-02-12

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) is an increasingly prevalent disease that is associated with multiple metabolic disturbances, yet the metabolic pathways underlying its progression are poorly understood. Here we studied metabolic pathways of the human liver across the full histological spectrum of NAFLD. We analyzed whole liver tissue transcriptomics and serum metabolomics data obtained from a large, prosp...

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Literature Corpus work
0e3e2fb6-451c-5d27-949e-7eb30cb01b90
DOI
10.1101/2021.02.09.21251354
Open publication

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Quantitative genome-scale analysis of human liver reveals dysregulation of glycosphingolipid pathways in progressive nonalcoholic fatty liver diseaseDOI 10.1101/2021.02.09.21251354
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