Article

A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy

2021-10-13

Abstract excerpt

Many SARS-CoV-2 variants have mutations at key sites targeted by antibodies. However, it is unknown if antibodies elicited by infection with these variants target the same or different regions of the viral spike as antibodies elicited by earlier viral isolates. Here we compare the specificities of polyclonal antibodies produced by humans infected with early 2020 isolates versus the B.1.351 variant of concern (also...

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Literature Corpus work: 0e3c6efe-62e6-5f00-b123-10ff5235819a
DOI: 10.1101/2021.10.12.464114

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