Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study

23 Sept 2021

Abstract excerpt

Antibody-based therapeutics and vaccines are essential to combat COVID-19 morbidity and mortality after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Multiple mutations in SARS-CoV-2 that could impair antibody defenses propagated in human-to-human transmission and spillover or spillback events between humans and animals. To develop prevention and therapeutic strategies, we formed an...

Topics

Join the communities discussing this publication.

SARS-CoV-2 and COVID-19 Research
vaccines and immunoinformatics approaches
Viral gastroenteritis research and epidemiology

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34554826
DOI: 10.1126/science.abh2315

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium studyPMID 34554826Read ↗

Potent neutralization of SARS-CoV-2 variants of concern by an antibody with a unique genetic signature and structural mode of spike recognitionSemantic proximity Read ↗

Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domainSemantic proximity Read ↗

The antigenic anatomy of SARS-CoV-2 receptor binding domainSemantic proximity Read ↗

Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike proteinSemantic proximity Read ↗

Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktailSemantic proximity Read ↗

COVID-19 Serum Drives Spike-Mediated SARS-CoV-2 Variation.Semantic proximity Read ↗

Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B.1.1.7 variant.Semantic proximity Read ↗

Insertion in the N-Terminal Domain of the SARS-CoV-2 Spike Glycoprotein Affects Antibody Recognition and Phenotypic Properties.Semantic proximity Read ↗

Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralizationSemantic proximity Read ↗

Delineating the functional activity of antibodies with cross-reactivity to SARS-CoV-2, SARS-CoV-1 and related sarbecovirusesSemantic proximity Read ↗

Delineating the functional activity of antibodies with cross-reactivity to SARS-CoV-2, SARS-CoV-1 and related sarbecovirusesSemantic proximity Read ↗

Defining the Antigenic Topology and Prospective Binding Breadth of Vaccination-induced SARS-CoV-2 Neutralizing AntibodiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.