Article

The balance of acidic and hydrophobic residues predicts acidic transcriptional activation domains from protein sequence

2023-02-11

Abstract excerpt

Transcription factors activate gene expression in development, homeostasis, and stress with DNA binding domains and activation domains. Although there exist excellent computational models for predicting DNA binding domains from protein sequence (Stormo, 2013), models for predicting activation domains from protein sequence have lagged behind (Erijman et al., 2020; Ravarani et al., 2018; Sanborn et al., 2021), parti...

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Literature Corpus work: 0e117606-531f-53d0-bc51-6d1695ac212e
DOI: 10.1101/2023.02.10.528081

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