Article

SREBP1 is associated with lipid-metabolic reprogramming and apoptotic regulation in pancreatic ductal adenocarcinoma

2026-06-01

Abstract excerpt

<title>Abstract</title> <p>Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies and remains associated with limited therapeutic options. Lipid metabolic reprogramming plays a critical role in tumor growth, adaptation to metabolic stress, and therapeutic resistance. However, the role of sterol regulatory element-binding protein 1(SREBP1), encoded by sterol regulatory element-b...

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Literature Corpus work: 0e080622-efdd-571a-b62c-be61723dedea
DOI: 10.21203/rs.3.rs-9770771/v1

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