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Mitochondrial Autophagy in Ischemic Aged Livers

16 Dec 2022

Abstract excerpt

Mitochondrial autophagy (mitophagy) is a central catabolic event for mitochondrial quality control. Defective or insufficient mitophagy, thus, can result in mitochondrial dysfunction, and ultimately cell death. There is a strong causal relationship between ischemia/reperfusion (I/R) injury and mitochondrial dysfunction following liver resection and transplantation. Compared to young patients, elderly patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36552847
DOI: 10.3390/cells11244083

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