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Advances in understanding the role of mitochondria in renal ischemia–reperfusion injury

8 Jul 2025

Abstract excerpt

Renal ischemia-reperfusion injury (RIRI) is a major cause of acute kidney failure. Recent studies have shown that RIRI mechanism is closely related to abnormal mitochondrial biogenesis, fusion, fission, and autophagy. Maintaining normal mitochondrial function is essential for RIRI treatment. Therefore, it is important to explore molecular mechanisms of RIRI and relevant therapeutic targets. This review describes...

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PMID: 40627278
DOI: 10.1007/s10157-025-02727-3

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