Article

The IL-33-ILC2 pathway protects from amebic colitis

2021-06-15

Abstract excerpt

Entamoeba histolytica is a pathogenic protozoan parasite that causes intestinal colitis, diarrhea, and in some cases, liver abscess. Through transcriptomics analysis, we observed that E. histolytica infection was associated with increased expression of IL-33 mRNA in both the human and murine colon. IL-33, the IL-1 family cytokine, is released after cell injury to alert the immune system of tissue damage during in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0d9fa456-9c0c-5775-a9dc-2787da6c0b32
DOI: 10.1101/2021.06.14.448450

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The IL-33-ILC2 pathway protects from amebic colitisDOI 10.1101/2021.06.14.448450Read

The Role of IL-33 in Gut Mucosal InflammationSemantic proximity Read

IL-33 and IL-33 Receptors in Host Defense and DiseasesSemantic proximity Read

Role of type 2 immunity in intestinal inflammationSemantic proximity Read

Signaling and functions of interleukin-33 in immune regulation and diseasesSemantic proximity Read

New dog and new tricks: evolving roles for IL-33 in type 2 immunitySemantic proximity Read

Interleukin‐33 in allergySemantic proximity Read

IL-33 regulates the IgA-microbiota axis to restrain IL-1α–dependent colitis and tumorigenesisSemantic proximity Read

The Evolutionary Role of the IL-33/ST2 System in Host Immune DefenceSemantic proximity Read

IL-33 protects from recurrent <i>C. difficile</i> infection by restoration of humoral immunitySemantic proximity Read

Active eosinophils regulate host defence and immune responses in colitisSemantic proximity Read

AntigenB drives M1/M2 polarization following Echinococcus granulosus infection in inflammatory bowel diseaseSemantic proximity Read

OLFM4 modulates intestinal inflammation by promoting IL-22+ILC3 in the gutSemantic proximity Read