Article

Determining gene specificity from multivariate single-cell RNA sequencing data

2025-11-24

Abstract excerpt

An important application of single-cell genomics experiments is to identify genes specific to biological categories or experimental conditions. Although numerous approaches have been proposed to identify such genes, we consider an axiomatic approach based on defining properties that a specificity measure should have. This leads us to develop ember (Entropy Metrics for Biological ExploRation), which we show is the...

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Literature Corpus work: 0d8d1203-d57f-54c6-929e-b1ef544e7101
DOI: 10.1101/2025.11.21.689845

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