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Development and Validation of a Multiplex Real-Time PCR Assay for Detection and Quantification of<i>Streptococcus pneumoniae</i>in Pediatric Respiratory Samples

2023-05-05

Abstract excerpt

Streptococcus pneumoniae ( Spn ) is a bacterial pathogen that causes a range of disease manifestations in children, from acute otitis media to pneumonia, septicemia, and meningitis. Primary Spn laboratory diagnostic identification methods include culture, antigen testing, single-plex real-time PCR, and syndromic PCR panels. However, each method lacks sensitivity, specificity, and/or cost efficiency. We developed a...

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Literature Corpus work
0d60840a-3e7d-57be-b847-b21ba7636726
DOI
10.1101/2023.05.03.23289397
Open publication

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Development and Validation of a Multiplex Real-Time PCR Assay for Detection and Quantification of<i>Streptococcus pneumoniae</i>in Pediatric Respiratory SamplesDOI 10.1101/2023.05.03.23289397
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