Utilizing large and diverse bacterial genome datasets to improve the detection and identification of Streptococcus pneumoniae via PCR-based diagnostics

Abstract excerpt

The accurate identification of Streptococcus pneumoniae (pneumococcus) is crucial for diagnostics and surveillance but is complicated by the use of molecular assays that may also detect non-pneumococcal Streptococcus (NPS) species. Therefore, the aim of this study was to use a combination of in silico and in vitro analyses to evaluate PCR assays for the molecular detection and identification of pneumococci. A...

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