Article

A physiologically-validated rat model of term birth asphyxia with seizure generation after, not during, brain hypoxia

2020-05-05

Abstract excerpt

<h4>ABSTRACT</h4> Birth asphyxia (BA) is often associated with seizures which emerge during the recovery and may exacerbate the ensuing hypoxic-ischemic encephalopathy. In rodent models of BA, exposure to hypoxia is used to evoke seizures, which commence already during the insult. Here, we introduce a term-equivalent model of BA, in which seizures are triggered after, not during, brain hypoxia. Postnatal day 11-1...

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Literature Corpus work: 0d3aafe6-d933-584c-a78c-f666e423194c
DOI: 10.1101/2020.05.05.078220

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