Article

A proteome-wide screen for membrane-interactions in intrinsically disordered regions of transmembrane proteins reveals a role in disease

2025-08-18

Abstract excerpt

<h4>Summary</h4> Transmembrane proteins mediate essential cellular processes including signaling, transport, and ion flux. Besides their well-characterized structured domains, most contain intrinsically disordered regions, whose biological roles remain poorly understood. Evidence suggests that the functions of intrinsically disordered regions are context-dependent, a trait particularly relevant when anchored to c...

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Literature Corpus work: 0d1ecf82-f3a0-5db2-9f52-81534bcef0a1
DOI: 10.1101/2025.08.15.670465

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