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Article

Sex-Dependent Gene Expression in Human Pluripotent Stem Cells

1 Aug 2014

Abstract excerpt

Males and females have a variety of sexually dimorphic traits, most of which result from hormonal differences. However, differences between male and female embryos initiate very early in development, before hormonal influence begins, suggesting the presence of genetically driven sexual dimorphisms. By comparing the gene expression profiles of male and X-inactivated female human pluripotent stem cells, we detected...

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PMID: 25127145
DOI: 10.1016/j.celrep.2014.07.013

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