Article

Upregulation of SGOL2 Predicts Poor Prognosis and Facilitates Hepatocellular Carcinoma Progression via Dysregulating the Cell Cycle by Directly Activating MAD2

2021-06-08

Abstract excerpt

<h4>Background: </h4> Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Shugoshin-like protein 2 (SGOL2) is a centromeric protein that ensures the correct and orderly process of mitosis by protecting and maintaining centripetal adhesions during meiosis and mitosis. However, the role of SGOL2 in cancer is not well understood. <h4>Methods:</h4> The mRNA and protein levels o...

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Literature Corpus work: 1c978874-2564-5a18-86f7-6ddddc4a3157
DOI: 10.21203/rs.3.rs-560609/v1

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