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Article

LASP2 is downregulated in human liver cancer and contributes to hepatoblastoma cell malignant phenotypes through MAPK/ERK pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jul 2020

Li Jing, Hu Shaojun, Zhang Zhiyong, Qian Lei, Xue Qing, Qu Xiusheng

Abstract excerpt

LASP2 was recently demonstrated to serve as multifaceted roles in several types of cancers. However, its underlying mechanism in the progression of human liver cancer has not been explored. The aims of the current study were to detect LASP2 expression in a liver tissue microarray, and to determine whether LASP2 contributes to malignant phenotypes of HepG2 human hepatoblastoma cells. Our results revealed that...

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PMID: 32325347
DOI: 10.1016/j.biopha.2020.110154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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