Article

Efficacy of Tecovirimat and Cidofovir Against MPXV-Induced Pneumonia, Skin Lesion, and Arthritis in the High-Risk Population-Relevant SCID Mouse Model

2025-04-23

Abstract excerpt

<title>Abstract</title> <p> On February 27, 2025, WHO maintained monkeypox as a PHEIC following its third round of assessment. Human monkeypox virus infection primarily manifests with fever, lymphadenopathy, and rash. Severe cases may develop pneumonia, encephalitis, myocarditis and arthritis. After evaluation of three murine models (ICR, IFNAR1 <sup>−/−</sup> , and SCID), we identified SCID mice as stable hos...

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Literature Corpus work: 0cea3c52-086a-5b4e-a549-1fe945ce8bc7
DOI: 10.21203/rs.3.rs-6483910/v1

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Efficacy of Tecovirimat and Cidofovir Against MPXV-Induced Pneumonia, Skin Lesion, and Arthritis in the High-Risk Population-Relevant SCID Mouse ModelDOI 10.21203/rs.3.rs-6483910/v1Read

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