Article

Minichromosome maintenance 6 protects against renal fibrogenesis by regulating DUSP6-mediated ERK/GSK-3β/Snail1 signaling

2023-01-30

Abstract excerpt

<h4>Background: </h4> Renal fibrosis is a major determinant of chronic kidney disease (CKD) and an inevitable outcome in all types of progressive CKD. Minichromosome maintenance 6 (MCM6) promotes the migration and invasive ability of tumor cells by regulating the epithelial-mesenchymal transition (EMT) cascade, but its exact biological function in kidney diseases remains unclear. In this study, we aim to explore t...

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Literature Corpus work: 0cddea4e-0bec-5114-911f-284623f2d7fa
DOI: 10.21203/rs.3.rs-2471576/v1

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