Article

Ultrarare missense and frameshift variants in the <i>TECTA</i> gene may involve tectorial membrane in familial Meniere disease

2022-03-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Meniere’s disease (MD) is an inner ear disease defined by episodes of vertigo associated with sensorineural hearing loss initially affecting low- to medium frequencies, tinnitus, and aural fullness. Familial aggregation has been reported in 9-10% of MD patients showing, mostly, an autosomal dominant inheritance pattern with incomplete penetrance. However, familial MD is a gene...

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Literature Corpus work: 0cc439b5-3d0c-5d45-bf98-5b341d3a8869
DOI: 10.1101/2022.02.18.22270926

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