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Article

Rare missense variants in MYO7A and OTOP2 genes in a South Korean Meniere's disease cohort.

Journal of medical genetics - 23 Jul 2026

Pham Mai T, Cruz-Granados Pablo, Nadar-Ponniah Prathamesh T, Chua Han Chow, Jang Seung Hyun, Gee Heon Yung, Jung Jinsei, Choi Jae Young, Kim Sung Huhn, Lopez-Escamez Jose A

Abstract excerpt

BACKGROUND: Meniere's disease (MD) is a polygenic condition defined by episodes of vertigo associated with sensorineural hearing loss and tinnitus. Genetic studies in familial MD in East Asian populations are limited, and the potential MD genes remain to be established in non-Finnish European populations. METHODS: By exome sequencing and rare variant analysis, we have searched for existing and novel genes...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42020305
DOI: 10.1136/jmg-2025-111426

Genes

OTOP2
MYO7A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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