Article

Nutrient competition predicts gut microbiome restructuring under drug perturbations

2024-08-06

Abstract excerpt

<h4>ABSTRACT</h4> Human gut commensal bacteria are routinely exposed to various stresses, including therapeutic drugs, and collateral effects are difficult to predict. To systematically interrogate community-level effects of drug perturbations, we screened stool-derived in vitro communities with 707 clinically relevant small molecules. Across ∼5,000 community–drug interaction conditions, compositional and metabo...

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Literature Corpus work: 0cb79731-8f83-5fbd-a388-28f81534d0b5
DOI: 10.1101/2024.08.06.606863

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