Article

Leveraging transcript quantification for fast computation of alternative splicing profiles

2014-09-04

Abstract excerpt

Alternative splicing plays an essential role in many cellular processes and bears major relevance in the understanding of multiple diseases, including cancer. High-throughput RNA sequencing allows genome-wide analyses of splicing across multiple conditions. However, the increasing number of available datasets represents a major challenge in terms of computation time and storage requirements. We describe SUPPA, a c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0c7b8157-cf22-5e36-a830-1fdd3101476b
DOI: 10.1101/008763

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Leveraging transcript quantification for fast computation of alternative splicing profilesDOI 10.1101/008763Read

<i>SplAdder</i> : Identification, quantification and testing of alternative splicing events from RNA-Seq dataSemantic proximity Read

Selecting differential splicing methods: Practical considerations for short-read RNA sequencingSemantic proximity Read

Selecting differential splicing methods: Practical considerationsSemantic proximity Read

Differential transcript usage from RNA-seq data: isoform pre-filtering improves performance of count-based methodsSemantic proximity Read

CLASS: Accurate and Efficient Splice Variant Annotation from RNA-seq ReadsSemantic proximity Read

SpliceDecoder: A High-Throughput Tool for Guiding the Functional Interpretation of Differential Splicing EventsSemantic proximity Read

A technology-agnostic long-read analysis pipeline for transcriptome discovery and quantificationSemantic proximity Read

Detection of alternative splicing: deep sequencing or deep learning?Semantic proximity Read

Exon inclusion signatures enable accurate estimation of splicing factor activitySemantic proximity Read

RNA sequencing depth guidelines for the study of alternative splicingSemantic proximity Read

Alternative splicing detection workflow needs a careful combination of sample prep and bioinformatics analysisSemantic proximity Read

TRAWLING: a Transcriptome Reference Aware of spLIciNG eventsSemantic proximity Read