Article

Differential transcript usage from RNA-seq data: isoform pre-filtering improves performance of count-based methods

2015-08-24

Abstract excerpt

Large-scale sequencing of cDNA (RNA-seq) has been a boon to the quantitative analysis of transcriptomes. A notable application is the detection of changes in transcript usage between experimental conditions. For example, discovery of pathological alternative splicing may allow the development of new treatments or better management of patients. From an analysis perspective, there are several ways to approach RNA-se...

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Literature Corpus work: b455db1a-0540-5eb2-a130-fbc6c14dbf6d
DOI: 10.1101/025387

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