Article

MUC17 mutations and methylation are associated with poor prognosis in adult-type diffuse glioma patients

2023-02-01

Abstract excerpt

Diffuse gliomas are tumors that arise from glial or glial progenitor cells. They are currently classified as astrocytoma isocitrate dehydrogenase (IDH)-mutant or oligodendroglioma IDH-mutant, and 1p/19q-codeleted, both slower-growing tumors, or glioblastoma (GBM), a more aggressive tumor. Despite advances in the diagnosis and treatment of gliomas, the median survival time after diagnosis of GBM remains low, approx...

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Literature Corpus work: 0c105b26-3d1e-5e53-8e26-5f3216299426
DOI: 10.1101/2023.01.30.23285200

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