Article
MUC17 mutations and methylation are associated with poor prognosis in adult-type diffuse glioma patients.
Journal of the neurological sciences - 15 Sept 2023
Machado Gabriel Cardoso, Ferrer Valéria Pereira
Abstract excerpt
Diffuse gliomas are tumors that arise from glial or glial progenitor cells. They are currently classified as astrocytoma isocitrate dehydrogenase (IDH)-mutant or oligodendroglioma IDH-mutant, and 1p/19q-codeleted, both slower-growing tumors, or glioblastoma (GBM), a more aggressive tumor. Despite advances in the diagnosis and treatment of gliomas, the median survival time after diagnosis of GBM remains low,...
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