Article

Modeling Type 1 Diabetes progression from single-cell transcriptomic measurements in human islets

2023-07-19

Abstract excerpt

Type 1 diabetes (T1D) is a chronic condition in which the insulin-producing beta cells are destroyed by immune cells. Research in the past few decades characterized the immune cells involved in disease pathogenesis and has led to the development of immunotherapies that can delay the onset of T1D by two years. Despite this progress, early detection of autoimmunity in individuals who will develop T1D remains a chall...

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Literature Corpus work: 0bfad4b6-84f3-57dd-9cf3-b01f7ce8e1f3
DOI: 10.1101/2023.07.19.549708

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