Article

Tracking evolutionary pressure on the SARS-CoV-2 polybasic furin cleavage site arginine dimer: 25-31 July, 2022, sample

2022-08-05

Abstract excerpt

This work is part of a longitudinal study on the evolutionary pressure at the arginine dimer of the SARS-CoV-2 S-protein polybasic furin cleavage site. When a virus precursor acquired that furin site, it was not only a huge gain-of-function, but it was also the origin of a species (SARS-CoV-2). At molecular level, the furin site opened up two conceptually highly opposed landscapes. First (favourable for the virus)...

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Literature Corpus work: 0bf7d8e7-d371-5c81-9971-c5ae08092626
DOI: 10.21203/rs.3.rs-1926268/v1

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