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Article

SARS-CoV-2 S Mutations: A Lesson from the Viral World to Understand How Human Furin Works.

International journal of molecular sciences - 1 Mar 2023

Cassari Leonardo, Pavan Angela, Zoia Giulia, Chinellato Monica, Zeni Elena, Grinzato Alessandro, Rothenberger Sylvia, Cendron Laura, Dettin Monica, Pasquato Antonella

Abstract excerpt

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the etiological agent responsible for the worldwide pandemic and has now claimed millions of lives. The virus combines several unusual characteristics and an extraordinary ability to spread among humans. In particular, the dependence of the maturation of the envelope glycoprotein S from Furin enables the invasion and replication of the virus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36902222
DOI: 10.3390/ijms24054791
PMCID: PMC10003014

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