Article

Synonymous base substitution in SARS-CoV-2 EE.2 lineage furin arginine CGG–CGG codons

2023-07-06

Abstract excerpt

This work has been carried out within the framework of a study on SARS-CoV-2 spike glycoprotein furin cleavage site evolution. The polybasic motif (originally PRRA) present at the S1/S2 junction has two arginine codons CGG–CGG, whose usage is rare in coronaviruses. It has no analogy in other “linage B” beta‐coronaviruses, including neither the Laos closest known relatives of virus behind covid. An hypothesis for t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 05229ddc-dfab-5b2c-841c-d0369af412e9
DOI: 10.21203/rs.3.rs-3139964/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Synonymous base substitution in SARS-CoV-2 EE.2 lineage furin arginine CGG–CGG codonsDOI 10.21203/rs.3.rs-3139964/v1Read

SARS-CoV-2 CQ.1 and CQ.1.1 lineage isolates: 100% synonymous base substitution at furin arginine CGG–CGG codonsSemantic proximity Read

SARS-CoV-2 codon usage bias at furin site clear up the origin. Landscape of Omicron sub-variants BA.4 and BA.5 (a July, 2022 sample)Semantic proximity Read

On-going evidence on SARS-CoV-2 furin site arginine codon usage bias and new found PRRA-like insertionsSemantic proximity Read

SARS-CoV-2 XBB.1.16.20 lineage study sample: 21% shows a synonymous base substitution in the S gene arginine codons CGG–CGG encoding the S protein furin cleavage siteSemantic proximity Read

SARS-CoV-2 is losing the CGG-CGG genetic footprint. Working sample of August 2022Semantic proximity Read

Tracking evolutionary pressure on the SARS-CoV-2 polybasic furin cleavage site arginine dimer: 25-31 July, 2022, sampleSemantic proximity Read

SARS-CoV-2 and the CGG-CGG Furin Site Genetic Fingerprint: Five Years LaterSemantic proximity Read

SARS-CoV-2 spike glycoprotein hotspots for RNA recombination provide insight into the probable human origin of the PRRA polybasic furin insertSemantic proximity Read

A piece in the SARS-CoV-2 genome mosaic: furin site on the spike proteinSemantic proximity Read

Perspectives: SARS-CoV-2 Spike Convergent Evolution as a Guide to Explore Adaptive Advantage.Semantic proximity Read

SARS-CoV-2 Origin: An Affair of Codons?Semantic proximity Read

Probable human origin of the SARS-CoV-2 polybasic furin cleavage siteSemantic proximity Read