Article

Reinforcement learning as an intermediate phenotype in psychosis? Deficits sensitive to illness stage but not associated with polygenic risk of schizophrenia in the general population

2019-06-13

Abstract excerpt

<h4>Background</h4> Schizophrenia is a complex disorder in which the causal relations between risk genes and observed clinical symptoms are not well understood and the explanatory gap is too wide to be clarified without considering an intermediary level. Thus, we aimed to test the hypothesis of a pathway from molecular polygenic influence to clinical presentation occurring via deficits in reinforcement learning....

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Literature Corpus work: 0bf6f077-9805-5db8-9c04-36dbe740a1dd
DOI: 10.1101/668939

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