Article
Associative learning and the genetics of schizophrenia.
Trends in neurosciences - 1 Jun 2009
Hall Jeremy, Romaniuk Liana, McIntosh Andrew M, Steele J Douglas, Johnstone Eve C, Lawrie Stephen M
Abstract excerpt
Several well-validated susceptibility genes for schizophrenia have now been identified. We suggest that these genes can be divided into two broad classes. Those in the first class have direct effects on synaptic plasticity mediated through actions at glutamatergic synapses; those in the second class impact on meso-limbic dopamine signalling. We argue that these genes have an interactive effect on risk for...
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